WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:protein activation cascade       ID:GO:0072376
C=83; O=8; E=0.30; R=27.12; rawP=4.67e-10; adjP=2.79e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
2  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
3  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
4  ENSG00000003436 NA TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 7035 ENSG00000003436
5  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178
6  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
7  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
8  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936


Database:biological process       Name:complement activation       ID:GO:0006956
C=64; O=7; E=0.23; R=30.77; rawP=2.51e-09; adjP=7.50e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
5  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
6  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
7  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:humoral immune response       ID:GO:0006959
C=124; O=7; E=0.44; R=15.88; rawP=2.58e-07; adjP=5.14e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
5  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
6  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
7  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:complement activation, classical pathway       ID:GO:0006958
C=50; O=5; E=0.18; R=28.13; rawP=8.74e-07; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
5  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:immunoglobulin mediated immune response       ID:GO:0016064
C=116; O=6; E=0.41; R=14.55; rawP=3.30e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
5  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
6  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:B cell mediated immunity       ID:GO:0019724
C=119; O=6; E=0.42; R=14.19; rawP=3.83e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
5  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
6  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:lymphocyte mediated immunity       ID:GO:0002449
C=177; O=7; E=0.63; R=11.13; rawP=2.85e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126561 NA STAT5A signal transducer and activator of transcription 5A 6776 ENSG00000126561
2  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
3  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
4  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
5  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
6  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
7  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:humoral immune response mediated by circulating immunoglobulin       ID:GO:0002455
C=66; O=5; E=0.23; R=21.31; rawP=3.53e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
4  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
5  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:biological process       Name:embryonic cranial skeleton morphogenesis       ID:GO:0048701
C=36; O=4; E=0.13; R=31.26; rawP=7.68e-06; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
2  ENSG00000170577 NA SIX2 SIX homeobox 2 10736 ENSG00000170577
3  ENSG00000180447 NA GAS1 growth arrest-specific 1 2619 ENSG00000180447
4  ENSG00000233608 NA TWIST2 twist homolog 2 (Drosophila) 117581 ENSG00000233608


Database:biological process       Name:leukocyte mediated immunity       ID:GO:0002443
C=220; O=7; E=0.78; R=8.95; rawP=1.19e-05; adjP=0.0007
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126561 NA STAT5A signal transducer and activator of transcription 5A 6776 ENSG00000126561
2  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
3  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
4  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
5  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
6  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
7  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:molecular function       Name:proteoglycan binding       ID:GO:0043394
C=17; O=2; E=0.06; R=35.96; rawP=0.0014; adjP=0.0518
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
2  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257


Database:molecular function       Name:heparan sulfate proteoglycan binding       ID:GO:0043395
C=13; O=2; E=0.04; R=47.03; rawP=0.0008; adjP=0.0518
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
2  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257


Database:molecular function       Name:transmembrane receptor protein tyrosine kinase activity       ID:GO:0004714
C=67; O=3; E=0.22; R=13.69; rawP=0.0014; adjP=0.0518
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
3  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601


Database:molecular function       Name:transmembrane receptor protein kinase activity       ID:GO:0019199
C=84; O=3; E=0.27; R=10.92; rawP=0.0026; adjP=0.0722
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
3  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601


Database:molecular function       Name:protein binding       ID:GO:0005515
C=7337; O=32; E=24.00; R=1.33; rawP=0.0165; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000144648 NA CCBP2 chemokine binding protein 2 1238 ENSG00000144648
2  ENSG00000112290 NA WASF1 WAS protein family, member 1 8936 ENSG00000112290
3  ENSG00000197965 NA MPZL1 myelin protein zero-like 1 9019 ENSG00000197965
4  ENSG00000151491 NA EPS8 epidermal growth factor receptor pathway substrate 8 2059 ENSG00000151491
5  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
6  ENSG00000149115 NA TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 85456 ENSG00000149115
7  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
8  ENSG00000180447 NA GAS1 growth arrest-specific 1 2619 ENSG00000180447
9  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
10  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
11  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
12  ENSG00000081307 NA UBA5 ubiquitin-like modifier activating enzyme 5 79876 ENSG00000081307
13  ENSG00000137809 NA ITGA11 integrin, alpha 11 22801 ENSG00000137809
14  ENSG00000100889 NA PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 5106 ENSG00000100889
15  ENSG00000126467 NA TSKS testis-specific serine kinase substrate 60385 ENSG00000126467
16  ENSG00000178718 NA RPP25 ribonuclease P/MRP 25kDa subunit 54913 ENSG00000178718
17  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
18  ENSG00000047457 NA CP ceruloplasmin (ferroxidase) 1356 ENSG00000047457
19  ENSG00000197903 NA HIST1H2BK histone cluster 1, H2bk 85236 ENSG00000197903
20  ENSG00000177628 NA GBA glucosidase, beta, acid 2629 ENSG00000177628
21  ENSG00000100504 NA PYGL phosphorylase, glycogen, liver 5836 ENSG00000100504
22  ENSG00000119655 NA NPC2 Niemann-Pick disease, type C2 10577 ENSG00000119655
23  ENSG00000233608 NA TWIST2 twist homolog 2 (Drosophila) 117581 ENSG00000233608
24  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
25  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
26  ENSG00000078246 NA TULP3 tubby like protein 3 7289 ENSG00000078246
27  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
28  ENSG00000126561 NA STAT5A signal transducer and activator of transcription 5A 6776 ENSG00000126561
29  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
30  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
31  ENSG00000170577 NA SIX2 SIX homeobox 2 10736 ENSG00000170577
32  ENSG00000167994 NA RAB3IL1 RAB3A interacting protein (rabin3)-like 1 5866 ENSG00000167994


Database:molecular function       Name:glycoprotein binding       ID:GO:0001948
C=61; O=2; E=0.20; R=10.02; rawP=0.0170; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
2  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257


Database:molecular function       Name:serine-type endopeptidase activity       ID:GO:0004252
C=155; O=3; E=0.51; R=5.92; rawP=0.0142; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:molecular function       Name:peptidase inhibitor activity       ID:GO:0030414
C=172; O=3; E=0.56; R=5.33; rawP=0.0186; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
2  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
3  ENSG00000003436 NA TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 7035 ENSG00000003436


Database:molecular function       Name:serine-type peptidase activity       ID:GO:0008236
C=177; O=3; E=0.58; R=5.18; rawP=0.0201; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
2  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
3  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178


Database:molecular function       Name:calcium ion binding       ID:GO:0005509
C=668; O=6; E=2.19; R=2.75; rawP=0.0211; adjP=0.1952
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000126561 NA STAT5A signal transducer and activator of transcription 5A 6776 ENSG00000126561
3  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
4  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
5  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
6  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888


Database:cellular component       Name:extracellular region       ID:GO:0005576
C=2140; O=20; E=7.28; R=2.75; rawP=1.36e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
2  ENSG00000047457 NA CP ceruloplasmin (ferroxidase) 1356 ENSG00000047457
3  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
4  ENSG00000003436 NA TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 7035 ENSG00000003436
5  ENSG00000159403 NA C1R complement component 1, r subcomponent 715 ENSG00000159403
6  ENSG00000119655 NA NPC2 Niemann-Pick disease, type C2 10577 ENSG00000119655
7  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
8  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
9  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783
10  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
11  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
12  ENSG00000078246 NA TULP3 tubby like protein 3 7289 ENSG00000078246
13  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
14  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
15  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
16  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
17  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178
18  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
19  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
20  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363


Database:cellular component       Name:extracellular region part       ID:GO:0044421
C=1099; O=14; E=3.74; R=3.75; rawP=1.37e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
3  ENSG00000047457 NA CP ceruloplasmin (ferroxidase) 1356 ENSG00000047457
4  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
5  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
6  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
7  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
8  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
9  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
10  ENSG00000003436 NA TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 7035 ENSG00000003436
11  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178
12  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
13  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
14  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783


Database:cellular component       Name:extracellular space       ID:GO:0005615
C=856; O=12; E=2.91; R=4.12; rawP=2.50e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
3  ENSG00000047457 NA CP ceruloplasmin (ferroxidase) 1356 ENSG00000047457
4  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
5  ENSG00000000971 NA CFH complement factor H 3075 ENSG00000000971
6  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
7  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
8  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
9  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
10  ENSG00000003436 NA TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 7035 ENSG00000003436
11  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178
12  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558


Database:cellular component       Name:lysosomal lumen       ID:GO:0043202
C=71; O=3; E=0.24; R=12.42; rawP=0.0018; adjP=0.0302
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
2  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783
3  ENSG00000177628 NA GBA glucosidase, beta, acid 2629 ENSG00000177628


Database:cellular component       Name:vacuolar lumen       ID:GO:0005775
C=75; O=3; E=0.26; R=11.76; rawP=0.0021; adjP=0.0302
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
2  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783
3  ENSG00000177628 NA GBA glucosidase, beta, acid 2629 ENSG00000177628


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=14; E=6.52; R=2.15; rawP=0.0042; adjP=0.0504
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000144648 NA CCBP2 chemokine binding protein 2 1238 ENSG00000144648
2  ENSG00000069966 NA GNB5 guanine nucleotide binding protein (G protein), beta 5 10681 ENSG00000069966
3  ENSG00000197965 NA MPZL1 myelin protein zero-like 1 9019 ENSG00000197965
4  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
5  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
6  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
7  ENSG00000167995 NA BEST1 bestrophin 1 7439 ENSG00000167995
8  ENSG00000151491 NA EPS8 epidermal growth factor receptor pathway substrate 8 2059 ENSG00000151491
9  ENSG00000137809 NA ITGA11 integrin, alpha 11 22801 ENSG00000137809
10  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
11  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
12  ENSG00000162687 NA KCNT2 potassium channel, subfamily T, member 2 343450 ENSG00000162687
13  ENSG00000180447 NA GAS1 growth arrest-specific 1 2619 ENSG00000180447
14  ENSG00000173040 NA EVC2 Ellis van Creveld syndrome 2 132884 ENSG00000173040


Database:cellular component       Name:proteinaceous extracellular matrix       ID:GO:0005578
C=360; O=5; E=1.22; R=4.08; rawP=0.0075; adjP=0.0771
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
3  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
4  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
5  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=10; E=4.30; R=2.33; rawP=0.0096; adjP=0.0864
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000144648 NA CCBP2 chemokine binding protein 2 1238 ENSG00000144648
2  ENSG00000197965 NA MPZL1 myelin protein zero-like 1 9019 ENSG00000197965
3  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
4  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
5  ENSG00000151491 NA EPS8 epidermal growth factor receptor pathway substrate 8 2059 ENSG00000151491
6  ENSG00000137809 NA ITGA11 integrin, alpha 11 22801 ENSG00000137809
7  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
8  ENSG00000112936 NA C7 complement component 7 730 ENSG00000112936
9  ENSG00000162687 NA KCNT2 potassium channel, subfamily T, member 2 343450 ENSG00000162687
10  ENSG00000180447 NA GAS1 growth arrest-specific 1 2619 ENSG00000180447


Database:cellular component       Name:anchored to membrane       ID:GO:0031225
C=144; O=3; E=0.49; R=6.13; rawP=0.0130; adjP=0.1040
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000122121 NA XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 7512 ENSG00000122121
2  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
3  ENSG00000180447 NA GAS1 growth arrest-specific 1 2619 ENSG00000180447


Database:cellular component       Name:extracellular matrix       ID:GO:0031012
C=426; O=5; E=1.45; R=3.45; rawP=0.0147; adjP=0.1058
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000140092 NA FBLN5 fibulin 5 10516 ENSG00000140092
3  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
4  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
5  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).